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Niloofar Nazari

@puffin_brave_43

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Prompt: A simple yet beautiful chart with an image of the Ajuga plant in english language and the stages of laboratory and animal work, including all sentences from this text: Background Ajuga species: Used in Persian medicine for joint pain, gout, and jaundice. Ajuga chamaecistus ssp. tomentella: Known as “komafitoos”, native to Iran. Objective Investigate the antioxidant and liver-protective effects of the aerial part extract on acetaminophen-induced toxicity in rats. Methods Sample: 36 rats, divided into 6 groups. Treatment: Control group: Normal saline. Other groups: Acetaminophen (500 mg/kg) for 7 days. Treatment with Ajuga extract (200, 400, 800 mg/kg) and Silymarin (100 mg/kg). Measurements: Blood: ALT, AST, alkaline phosphatase, bilirubin, total protein, albumin. Liver tissue: Glutathione, malondialdehyde. Results Hepato-protective effects: Reduced liver damage enzymes. Lipid profile: Lower cholesterol, triglycerides, LDL, VLDL in treated groups. Best effects: 200 mg/kg extract significantly prevented glutathione decrease and malondialdehyde increase. Histopathology: Least damage at 200 mg/kg dose and silymarin. Conclusion Ajuga extract (200 mg/kg): Best liver-protective effects, improved fat profile compared to silymarin.